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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE4A All Species: 32.73
Human Site: S392 Identified Species: 51.43
UniProt: Q14139 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14139 NP_004779.2 1066 122561 S392 L K N L L Q L S P E T K H C I
Chimpanzee Pan troglodytes XP_001161169 1066 122495 S392 L K N L L Q L S P E T K H C I
Rhesus Macaque Macaca mulatta XP_001097812 1067 122494 S392 L K N L L Q L S P E T K H C I
Dog Lupus familis XP_850081 1066 122542 S392 L K N L L Q L S P E T K H C I
Cat Felis silvestris
Mouse Mus musculus Q9ES00 1173 133285 N521 I L H S I L L N G E T R E A A
Rat Rattus norvegicus Q6P7A2 1066 122361 S392 L K N L L Q L S P E T K H G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026081 1074 123247 S393 L K N L L Q L S P E T K H R I
Frog Xenopus laevis NP_001084506 1072 122544 S391 L K N L L Q L S P D T K H R I
Zebra Danio Brachydanio rerio XP_001922961 1078 122949 S397 L K N L L Q Q S G E T R H L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609060 993 113046 C361 T A V L V R L C A P L C M P S
Honey Bee Apis mellifera XP_393070 965 109934 F340 N A Q N D V S F S S M L C V S
Nematode Worm Caenorhab. elegans Q09349 980 113212 R362 I I S T N D I R T R S H Y D P
Sea Urchin Strong. purpuratus XP_786748 942 107668 S358 F R S L F K S S L E I R N R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LF41 1038 117510 A397 D K I D P K Y A F C G H R L K
Baker's Yeast Sacchar. cerevisiae P54860 961 109887 D338 Y K K I D K I D A N Y F N N P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.1 98.6 N.A. 24.6 97 N.A. N.A. 87.7 79.7 76.7 N.A. 33.1 36.5 22.9 32.7
Protein Similarity: 100 100 98.5 99.4 N.A. 45.2 99 N.A. N.A. 94.3 90.8 87.4 N.A. 51.3 54.5 42.5 52.2
P-Site Identity: 100 100 100 100 N.A. 20 93.3 N.A. N.A. 93.3 86.6 66.6 N.A. 13.3 0 0 20
P-Site Similarity: 100 100 100 100 N.A. 53.3 93.3 N.A. N.A. 93.3 93.3 80 N.A. 26.6 0 33.3 60
Percent
Protein Identity: N.A. N.A. N.A. 25.3 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 43.9 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 0 0 0 0 7 14 0 0 0 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 7 0 7 0 7 7 27 0 % C
% Asp: 7 0 0 7 14 7 0 7 0 7 0 0 0 7 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 60 0 0 7 0 0 % E
% Phe: 7 0 0 0 7 0 0 7 7 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 14 0 7 0 0 7 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 14 54 0 0 % H
% Ile: 14 7 7 7 7 0 14 0 0 0 7 0 0 0 47 % I
% Lys: 0 67 7 0 0 20 0 0 0 0 0 47 0 0 7 % K
% Leu: 54 7 0 67 54 7 60 0 7 0 7 7 0 14 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 0 % M
% Asn: 7 0 54 7 7 0 0 7 0 7 0 0 14 7 0 % N
% Pro: 0 0 0 0 7 0 0 0 47 7 0 0 0 7 14 % P
% Gln: 0 0 7 0 0 54 7 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 0 0 0 7 0 7 0 7 0 20 7 20 0 % R
% Ser: 0 0 14 7 0 0 14 60 7 7 7 0 0 0 14 % S
% Thr: 7 0 0 7 0 0 0 0 7 0 60 0 0 0 0 % T
% Val: 0 0 7 0 7 7 0 0 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 7 0 0 0 7 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _